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Malaria exhibits tremendous antigenic variation, both within single infections and across the parasite population, and variant-specific exposure is a strong predictor of future responses.
Public health campaigns attempt to drive the effective reproduction number close to unity.
This paper presents an algorithm to form heterosexual relationships of a desired joint age–mixing distribution. It includes control of the rates at which individuals seek new relationshi
This paper presents a mechanistic intrahost model and model-based simulations of the dynamics of P. falciparum.
Mathematical modelling is used to investigate the potential impact of treatment on HIV incidence but substantial uncertainties will remain because information on all the factors that could influenc
Several mathematical models that simulate HIV infection and disease progression have been developed to investigate the impact of expanding access to ART on the incidence of HIV (the number of new i
The EMOD model for HIV was compared to several other HIV models in an article by Eaton et al. published in PLoS Medicine.
Malaria is an important global health issue and basic vector ecology is a fundamental driver of transmission patterns, and changes in land usage or land modification can dramatically change transmi
Mathematical modeling can guide all stages of malaria elimination and eradication by synthesizing information, quantifying uncertainty, and extrapolating current knowledge.