The Leaky Vaccine dashboard is an online tool to explore the effects of exposure heterogeneity on HIV vaccine efficacy, given a leaky vaccine. A potential outcome of pathogen exposure heterogeneity (i.e. variation among individuals in the risk of getting infected) is that vaccine efficacy measured from a trial (i.e. the clinical efficacy) is lower than the biological vaccine efficacy (i.e. the per-exposure or per-contact vaccine efficacy). This distinction, between the per-exposure vaccine efficacy and the clinical efficacy of the same vaccine, is the focus of this tool.
Features
Features of HIV Leaky Vaccine include:
- Exploration of vaccine efficacy: The dashboard allows users to explore how a leaky vaccine (a vaccine that does not provide full immunity) impacts HIV vaccine efficacy.
- Focus on exposure heterogeneity: The tool analyzes the effects of different levels of exposure to HIV on vaccine performance, providing insights into how varying exposure rates influence vaccine outcomes.
- Online accessibility: The dashboard is available as an online tool, offering easy access for users to model and visualize the impact of vaccine parameters on HIV prevention efforts.
Our approach
Our approach utilizes interactive dashboards to enable users to explore complex data and scenarios directly through a web browser. We allow researchers and policymakers to visualize and manipulate various parameters to understand their effects on public health outcomes. These dashboards are designed to be user-friendly and adaptable.
