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Wesley earned his PHD at Harvard University under Dr. Dyann Wirth, Dr. Daniel L Hartl, and Daniel E. Neafsey where he used computational biology and bioinformatic techniques to study malaria genomics. He is interested in studying infectious disease evolution with models combining traditional population genetics and epidemiology. At IDM, he works with Mike Famulare to create dynamic models aimed at exploring multiscale transmission and viral evolution.